Cook lasagna noodles according to package directions; drain and set aside.
In a large skillet, brown beef, onion, and mushrooms.
Stir in spaghetti sauce, garlic powder, salt, oregano, and basil.
In a 2-quart baking dish (about 11x7x2 inches) greased with cooking spray, layer 1/3 of the ricotta cheese, Monterey Jack cheese, and Parmesan cheeses.
Repeat layers twice.
Bake lasagna for 30 minutes or until thoroughly heated and bubbly.